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B.M. Hatfield, C.A. Weidmann, C.A. McCutchin, P.S. Irving, I.N. Nelson, S. Felder and K.M. Weeks, Functional proximity across an mRNA. Biochemistry 64, in press (2025).</p> 330<p>170. M. Yang, R.P. Prestwood, L.F.M. Passalacqua, S. Balaratnam, C.R. Fullenkamp, J.W. Arney, K.M. Weeks, A. Ferre-D’Amare and J.S. Schneekloth, <a href="https://pubmed.ncbi.nlm.nih.gov/40437193/">Structure-informed design of an ultrabright RNA-activated fluorophore</a>. Nature Chem. 17, online (2025).</p> 331<p>169. J.M. Waldern, C. Taylor, C.A. Giannetti, P.S. Irving, S.R. Allen, M. Zhu, R. Backofen, D.H. Mathews, K.M. Weeks and A. Laederach, <a href="https://pubmed.ncbi.nlm.nih.gov/40396491/">Structural determinants of inverted Alu-mediated backsplicing revealed by -MaP and -JuMP</a>. Nucleic Acids Res. 53, gkaf433 (2025).</p> 332<p>168. X. Hao, Y. Chen, D. Sahu, R.K. Przanowska, M. Aaiyas, C.A. Weidmann, I. Nardi, K.M. Weeks and A. Dutta, <a href="https://pubmed.ncbi.nlm.nih.gov/40320073/">A 36-base hairpin within lncRNA DRAIC, which is modulated by alternative splicing, interacts with the IKKα coiled-coil domain and inhibits NF-κB and tumor cell phenotypes</a>. J. Biol. Chem. 301, 110172 (2025).</p> 333<p>167. S.D. Veenbaas, J.T. Koehn, P.S. Irving, N.N. Lama and Kevin M. Weeks, <a href="https://pubmed.ncbi.nlm.nih.gov/40261926/">Ligand-binding pockets in RNA, and where to find them</a>. Proc. Natl. Acad. Sci. USA 122, e2422346122 (2025).</p> 334<p>166. S. Felder, I.N. Nelson, B.M. Hatfield and K.M. Weeks, <a href="https://pubmed.ncbi.nlm.nih.gov/39662963/">Protein binding in an mRNA 5′-UTR sterically hinders translation</a>. RNA 31, 143-149 (2025).</p> 335<h3>2024</h3> 336<p>165. O. Anczukow, F.H. Allain, B.L. Angarola, D.L. Black, A.N. Brooks, C. Cheng, A. Conesa, E.I Crosse, E. Eyras, E. Guccione, S.X. Lu, K.M. Neugebauer, P. Sehgal, X. Song, Z. Tothova, J. Valcárcel, K.M. Weeks, G.W. Yeo and A. Thomas-Tikhonenko, <a href="https://pubmed.ncbi.nlm.nih.gov/39384951/">Steering research on mRNA splicing in cancer towards clinical translation</a>. Nature Rev. Cancer 24, 887-905 (2024).</p> 337<p>164. A.C. Tan, P.S Irving, J.T. Koehn, S. Jin, D.Y. Qiu and K.M. Weeks, <a href="https://pubmed.ncbi.nlm.nih.gov/39359229/">Fingerprinting Tertiary Structure in Complex RNAs Using Single-Molecule Correlated Chemical Probing</a>. Biochemistry 63, 2648-2657 (2024).</p> 338<p class="citation">163. J.W. Arney, A. Laederach, and K.M. Weeks, <a href="https://pubmed.ncbi.nlm.nih.gov/39024941/">Visualizing RNA structure ensembles by single-molecule correlated chemical probing</a>. Curr. Opin. Struct. Biol. 88, 102877 (2024)</p> 339<p class="citation">162. P.S. Irving and K.M. Weeks, <a href="https://pubmed.ncbi.nlm.nih.gov/38348910/">RNAvigate: Efficient exploration of RNA chemical probing datasets</a>. Nucl. Acids Res. 52 (5), 2231-2241 (2024)</p> 340<p class="citation">161. L. Chen, N.T. Ingolia, M.L. Insco, J.B. Li, S. Oberdoerffer, and K.M. Weeks, <a href="https://pubmed.ncbi.nlm.nih.gov/38242091/">Voices: challenges and opportunities in RNA biology</a>. Cell Chem. Biol. 30, 10-13 (2024)</p> 341<p class="citation">160. B.M. Hatfield, C.A. Weidmann and K.M. Weeks, <a href="https://pubmed.ncbi.nlm.nih.gov/37824069/">Measuring proximity-mediated function of mRNA regulatory proteins by engineered tethering</a><a href="https://doi.org/10.1007/978-1-0716-3481-3_9#DOI">.</a> Methods Mol. Biol. 2723, 143-159 (2024). <a href="https://weekslab.org/wp-content/uploads/sites/4127/2023/12/2023_bh_mimb.pdf" aria-label="Publication number 161 PDF">pdf</a></p> 342<h3 class="year">2023</h3> 343<p class="citation">159. Y. Xiang, W. Huang, L. Tan, T. Chen, Y. He, P.S. Irving, K.M. Weeks, Q.C. Zhang and X. Dong, <a href="https://pubmed.ncbi.nlm.nih.gov/37674078/">Pervasive downstream RNA hairpins dynamically dictate start-codon selection</a>. Nature. 621, 423â430 (2023) <a href="https://weekslab.org/wp-content/uploads/sites/4127/2023/12/2023_w_xd_nature.pdf" aria-label="Publication number 160 PDF">pdf</a></p> 344<p class="citation">158. M.A. Boerneke, N.S. Gokhale, S.M. Horner and K.M. Weeks, <a href="https://pubmed.ncbi.nlm.nih.gov/37011200/">Structure-first identification of RNA elements that regulate dengue virus genome architecture and replication</a>. Proc. Natl. Acad. Sci. USA 120, e2217053120 (2023). <a href="https://weekslab.org/wp-content/uploads/sites/4127/2023/07/2023_mb_pnas.pdf" aria-label="Publication number 158 PDF">
344pdf</a></p> 345<p class="citation">157. A.M. Mustoe, C.A. Weidmann and K.M. Weeks, <a href="https://pubmed.ncbi.nlm.nih.gov/36917683/">Single-molecule correlated chemical probing: A revolution in RNA structure analysis</a>. Acc. Chem. Res. 56, 763-775 (2023). <a href="https://weekslab.org/wp-content/uploads/sites/4127/2023/07/2023_am_cw_acr.pdf" aria-label="Publication number 157 PDF">pdf</a></p> 346<p class="citation">156. J.T. Koehn, S. Felder and K.M. Weeks, <a href="https://pubmed.ncbi.nlm.nih.gov/36863268/">Innovations in targeting RNA, by fragment-based ligand discovery</a>. Curr. Opin. Struct. Biol. 79, 102550 (2023). <a href="https://weekslab.org/wp-content/uploads/sites/4127/2023/07/2023_jk_sf_cosb.pdf" aria-label="Publication number 156 PDF">pdf</a></p> 347<h3 class="year">2022</h3> 348<p class="citation">155. P.J. Grayeski, C.A. Weidmann, J. Kumar, L. Lackey, A.M. Mustoe, S. Busan, A. Laederach and K.M. Weeks, <a href="https://pubmed.ncbi.nlm.nih.gov/36107773/">Global 5′-UTR RNA structure regulates translation of a SERPINA1 mRNA</a>. Nucl. Acids Res. 50, 9689-9704 (2022). <a href="https://weekslab.org/wp-content/uploads/sites/4127/2023/07/2022_pg_nar.pdf" aria-label="Publication number 155 PDF">pdf</a></p> 349<p class="citation">154. C.A. Roden, Y. Dai, C.A. Giannetti, I. Seim, M. Lee, R. Sealfon, G.A. McLaughlin, M.A. Boerneke, C. Iserman, S.A. Wey, J.L Ekena, O.G. Troyanskaya, K.M. Weeks, L. You, A. Chilkoti and A.S. Gladfelter, <a href="https://pubmed.ncbi.nlm.nih.gov/35871289/">Double-stranded RNA drives SARS-CoV-2 nucleocapsid protein to undergo phase separation at specific temperatures</a>. Nucl. Acids Res. 50, 8168-8192 (2022). <a href="https://weekslab.org/wp-content/uploads/sites/4127/2023/07/2022_w_ag_nar.pdf" aria-label="Publication number 154 PDF">pdf</a></p> 350<p class="citation">153. J.W. Arney and K.M. Weeks, <a href="https://pubmed.ncbi.nlm.nih.gov/35802500/">RNA-ligand interactions quantified by surface plasmon resonance with reference subtraction</a>. Biochemistry 61, 1625-1632 (2022). <a href="https://weekslab.org/wp-content/uploads/sites/4127/2023/07/2022_wa_bch.pdf" aria-label="Publication number 153 PDF">pdf</a></p> 351<p class="citation">152. J. Kumar, L. Lackey, J.M. Waldern, A. Dey, A.M. Mustoe, K.M. Weeks, D.H. Mathews and A. Laederach, <a href="https://pubmed.ncbi.nlm.nih.gov/35695373/">Quantitative prediction of variant effects on alternative splicing in MAPT using endogenous pre-messenger RNA structure probing</a>. eLife 11, e73888 (2022). <a href="https://weekslab.org/wp-content/uploads/sites/4127/2023/07/2022_w_al_elife.pdf" aria-label="Publication number 152 PDF">pdf</a></p> 352<p class="citation">151. M.J. Zeller, O. Favorov, K. Li, A. Nuthanakanti, D. Hussein, A. Michaud, D.A. Lafontaine, S. Busan, A. Serganov, J. Aubé and Kevin M. Weeks, <a href="https://pubmed.ncbi.nlm.nih.gov/35561226/">SHAPE-enabled fragment-based ligand discovery for RNA</a>. Proc. Natl. Acad. Sci. USA 119, e2122660119 (2022). <a href="https://weekslab.org/wp-content/uploads/sites/4127/2023/07/2022_mz_pnas.pdf" aria-label="Publication number 151 PDF">pdf</a></p> 353<p class="citation">150. S.W. Olson, A.-M.W. Turner, J.W. Arney, I. Saleem, C.A. Weidmann, D.M. Margolis, K.M. Weeks and A.M. Mustoe, <a href="https://pubmed.ncbi.nlm.nih.gov/35320755/">Discovery of a large-scale, cell-state-responsive allosteric switch in the 7SK RNA using DANCE-MaP</a>. Mol. Cell 82, 1708-1723 (2022). <a href="https://weekslab.org/wp-content/uploads/sites/4127/2023/07/2022_so_molcell.pdf" aria-label="Publication number 150 PDF">pdf</a></p> 354<p class="citation">149. M.J. Zeller, A. Nuthanakanti, K. Li, J. Aubé, A. Serganov and K.M. Weeks, <a href="https://pubmed.ncbi.nlm.nih.gov/35060698/">Subsite Ligand Recognition and Cooperativity in the TPP Riboswitch: Implications for Fragment-Linking in RNA Ligand Discovery</a>. ACS Chem. Biol. (2022). <a href="https://weekslab.org/wp-content/uploads/sites/4127/2022/02/2022_mz_acschembiol.pdf" aria-label="Publication number 149 PDF">pdf</a></p> 355<p class="citation">148. W. Stephenson, R. Razaghi, S. Busan, K.M. Weeks, W. Timp and P. Smibert, <a href="https://pubmed.ncbi.nlm.nih.gov/35252946/">Direct detection of RNA modifications and structure using single-molecule nanopore sequencing</a>. Cell Genomics 2, 100097 (2022). <a href="https://weekslab.org/wp-content/uploads/sites/4127/2023/07/2022_w_ws_cellgen.pdf" aria-label="Publication number 148 PDF">pdf</a></p> 356<p class="citation">147. R.K. Przanowska, C.A. Weidmann, S. Saha, M.A. Cichewicz, K.N. Jensen, P. Przanowski, P.S. Irving, K.A. Janes, M.J. Guertin, K.M. Weeks and A. Dutta, <a href="https://pubmed.ncbi.nlm.nih.gov/35172143/">Distinct MUNC lncRNA structural domains regulate transcription of different promyogenic factors</a>. Cell Rep. 38, 110361 (2022). <a href="https://weekslab.org/wp-content/uploads/sites/4127/2023/07/2022_w_ad_cellrep.pdf" aria-label="Publication number 147 PDF">pdf</a></p> 357<h3 class="year">2021</h3> 358<p class="citation">146. K.M. Weeks, <a href="https://pubmed.ncbi.nlm.nih.gov/34446594/">Piercing the fog of the RNA structure-ome</a>. <span class="italics">Science</span> <span class="bold">373</span>, 964-965 (2021). <a href="https://weekslab.org/wp-content/uploads/sites/4127/2021/09/2021_kw_science.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 146 PDF">pdf</a></p> 359<p class="citation">145. T.W. Christy, C.A. Giannetti, A. Laederach and K.M. Weeks, <a href="https://pubmed.ncbi.nlm.nih.gov/34905538/">Identifying proximal RNA interactions from cDNA-encoded crosslinks with ShapeJumper</a>. PLoS Comput. Biol. 17, e1009632 (2021). <a href="https://weekslab.org/wp-content/uploads/sites/4127/2022/02/2021_tc_pcompbiol.pdf" aria-label="Publication number 145 PDF">pdf</a></p> 360<p class="citation">144. T.W. Christy, C.A. Giannetti, G. Houlihan, M.J. Smola, G.M. Rice, J. Wang, N.V. Dokholyan, A. Laederach, P. Holliger and K.M. Weeks, <a href="https://pubmed.ncbi.nlm.nih.gov/34121404/">Direct mapping of higher-order RNA interactions by SHAPE-JuMP</a>. Biochemistry 60, 1971-1982 (2021). <a href="https://weekslab.org/wp-content/uploads/sites/4127/2021/09/2021_tc_bch.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 144 PDF">
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Mauger, M. Golden, D. Yamane, S. Willford, S.M. Lemon, D.P. Martin and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/25775547">The functionally conserved architecture of hepatitis C virus RNA genomes</a>. <span class="italics">Proc. Natl. Acad. Sci. USA</span> <span class="bold">112</span>, 3692-3697 (2015). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2015_dm_pnas.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 106 PDF">pdf</a> | <a href="https://webshare.oasis.unc.edu/weeksgroup/data-files/hcv_genome_DATA.zip" target="_blank" rel="noopener noreferrer" aria-label="Publication number 106 zipped data download">data</a></p> 406<p class="citation">105. J.L. McGinnis, Q. Liu, C.A. Lavender, A. Devaraj, S.P. McClory, K. Fredrick and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/25675474">In-cell SHAPE reveals that free 30S ribosome subunits are in the inactive state</a>. <span class="italics">Proc. Natl. Acad. Sci. USA</span> <span class="bold">112</span>, 2425-2430 (2015). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2015_jm_pnas.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 105 PDF">pdf</a> | <a href="https://webshare.oasis.unc.edu/weeksgroup/data-files/rbsome_in_vivo_DATA.zip" target="_blank" rel="noopener noreferrer" aria-label="Publication number 105 zipped data download">data</a></p> 407<p class="citation">104. C.A. Lavender, R.J. Gorelick and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/25992893">Structure-based alignment and consensus secondary structures for three HIV-related RNA genomes</a>. <span class="italics">PLoS Comput. Biol.</span> <span class="bold">11</span>, e1004230 (2015). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2015_al_pcbi_2.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 104 PDF">pdf</a> | <a href="https://webshare.oasis.unc.edu/weeksgroup/data-files/align_hiv_DATA.zip" target="_blank" rel="noopener noreferrer" aria-label="Publication number 104 zipped data download">data</a></p> 408<p class="citation">103. C.A. Lavender, R. Lorenz, G. Zhang, R. Tamayo, I.L. Hofacker and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/25992778">Model-free RNA sequence and structure alignment informed by SHAPE probing reveals a conserved alternative secondary structure for 16S rRNA</a>. <span class="italics">PLoS Comput. Biol.</span> <span class="bold">11</span>, e1004126 (2015). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2015_al_pcbi_1.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 103 PDF">
408pdf</a> | <a href="https://webshare.oasis.unc.edu/weeksgroup/data-files/align_1_DATA.zip" target="_blank" rel="noopener noreferrer" aria-label="Publication number 103 zipped data download">data</a></p> 409<p class="citation">102. K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/25546503">Toward all RNA structures, concisely</a>. <span class="italics">Biopolymers</span> <span class="bold">103</span>, 438-448 (2015). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2015_kw_biop.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 102 PDF">pdf</a></p> 410<p class="citation">101. A.I. Taylor, V.B. Pinheiro, M.J. Smola, A.S. Morgunov, S. Peak-Chew, C. Cozens, K.M. Weeks, P. Herdewijn & P. Holliger, <a href="https://www.ncbi.nlm.nih.gov/pubmed/25470036">Catalysts from synthetic genetic polymers</a>. <span class="italics">Nature</span> <span class="bold">518</span>, 427-430 (2015). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2015_at_ms_nature.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 101 PDF">pdf</a></p> 411<h3 class="year">2014</h3> 412<p class="citation">100. P.J. Homan, A. Tandon, G.M. Rice, F. Ding, N.V. Dokholyan and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/25341083">RNA tertiary structure analysis by 2′-hydroxyl molecular interference</a>. <span class="italics">Biochemistry</span> <span class="bold">53</span>, 6825-6833 (2014). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2014_ph_bch.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 100 PDF">pdf</a></p> 413<p class="citation">99. P.J. Homan, O.V. Favorov, C.A. Lavender, O. Kursun, X. Ge, S. Busan, N.V. Dokholyan and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/25205807">Single-molecule correlated chemical probing of RNA</a>. <span class="italics">Proc. Natl. Acad. Sci. USA</span> <span class="bold">111</span>, 13858-13863 (2014). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2014_ph_pnas.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 99 PDF">pdf</a> | <a href="https://webshare.oasis.unc.edu/weeksgroup/data-files/ring-map_DATA.zip" target="_blank" rel="noopener noreferrer" aria-label="Publication number 99 zipped data download">data</a> | <a href="https://weekslab.org/software" target="_blank" rel="noopener noreferrer">software</a></p> 414<p class="citation">98. N.A. Siegfried, S. Busan, G.M. Rice, J.A.E. Nelson and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/25028896">RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP)</a>. <span class="italics">Nature Meths.</span> <span class="bold">11</span>, 959-965 (2014). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2014_ns_nmeths.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 98 PDF">pdf</a> | <a href="https://webshare.oasis.unc.edu/weeksgroup/data-files/shape-map_DATA.zip" target="_blank" rel="noopener noreferrer" aria-label="Publication number 98 zipped data download">data</a> | <a href="https://weekslab.org/software" target="_blank" rel="noopener noreferrer">software</a></p> 415<p class="citation">97. J.T. Low, P. Garcia-Miranda, K.D. Mouzakis, R.J. Gorelick, S.E. Butcher and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/24926888">Structure and dynamics of the HIV-1 frameshift element RNA</a>. <span class="italics">Biochemistry</span> <span class="bold">53</span>, 4282-4291 (2014). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2014_jl_bch.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 97 PDF">pdf</a></p> 416<p class="citation">96. G.M. Rice, S. Busan, F. Karabiber, O.V. Favorov and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/25432749">SHAPE analysis of small RNAs and riboswitches</a>. <span class="italics">Methods Enzymol.</span> <span class="bold">549</span>, 165-187 (2014). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2014_gr_sb_mie.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 96 PDF">pdf</a> | <a href="https://weekslab.org/software" target="_blank" rel="noopener noreferrer">software</a></p> 417<p class="citation">95. J.L. McGinnis and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/24818530">Ribosomal RNA assembly intermediates visualized in living cells</a>. <span class="italics">Biochemistry</span> <span class="bold">53</span>, 3237-3247 (2014). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2014_jm_bch.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 95 PDF">pdf</a> | <a href="https://webshare.oasis.unc.edu/weeksgroup/data-files/rbsome_trxn_DATA.zip" target="_blank" rel="noopener noreferrer" aria-label="Publication number 95 zipped data download">data</a></p> 418<p class="citation">94. K.D. Warner, P. Homan, K.M. Weeks, A.G. Smith, C. Abell & A.R. Ferré-D’Amaré, <a href="https://www.ncbi.nlm.nih.gov/pubmed/24768306">Validating fragment-based drug discovery for biological RNAs: Lead fragments bind and remodel the TPP riboswitch specifically</a>. <span class="italics">Chem. Biol.</span> <span class="bold">21</span>, 591-595 (2014). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2014_kd_ph_chemb.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 94 PDF">
418pdf</a></p> 419<p class="citation">93. J.K. Grohman, R.J. Gorelick, S. Kottegoda, N.L. Allbritton, A. Rein and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/24623442">An immature retroviral RNA genome resembles a kinetically trapped intermediate state</a>. <span class="italics">J. Virol.</span> <span class="bold">88</span>, 6061â6068 (2014). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2014_jg_jvi.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 93 PDF">pdf</a></p> 420<p class="citation">92. G.M. Rice, C.W. Leonard and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/24742934">RNA secondary structure modeling at consistent high accuracy using differential SHAPE</a>. <span class="italics">RNA</span> <span class="bold">20</span>, 846-854 (2014). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2014_gr_rna.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 92 PDF">pdf</a> | <a href="https://webshare.oasis.unc.edu/weeksgroup/data-files/diff_shape_DATA.zip" target="_blank" rel="noopener noreferrer" aria-label="Publication number 92 zipped data download">data</a> | <a href="https://weekslab.org/software" target="_blank" rel="noopener noreferrer">software</a></p> 421<h3 class="year">2013</h3> 422<p class="citation">91. J. Tyrrell, J.L. McGinnis, K.M. Weeks and G.J. Pielak, <a href="https://www.ncbi.nlm.nih.gov/pubmed/24215455">The cellular environment stabilizes adenine riboswitch RNA structure</a>. <span class="italics">Biochemistry</span> <span class="bold">52</span>, 8777-8785 (2013). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2013_jt_bch.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 91 PDF">pdf</a></p> 423<p class="citation">90. S. Busan and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/24199621">The role of context in RNA structure: flanking sequences reconfigure CAG motif folding in huntingtin exon 1 transcripts</a>. <span class="italics">Biochemistry</span> <span class="bold">52</span>, 8219-8225 (2013). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2013_sb_bch.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 90 PDF">pdf</a></p> 424<p class="citation">89. E.J. Archer, M.A. Simpson, N.J. Watts, R. O’Kane, B. Wang, D.A. Erie, A. McPherson and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/23614526">Long-range architecture in a viral RNA genome</a>. <span class="italics">Biochemistry</span> <span class="bold">52</span>, 3182-3190 (2013). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2013_utp_bch.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 89 PDF">pdf</a> | <a href="https://webshare.oasis.unc.edu/weeksgroup/data-files/STMV_DATA.zip" target="_blank" rel="noopener noreferrer" aria-label="Publication number 89 zipped data download">data</a></p> 425<p class="citation">88. E. Pollom, K.K. Dang, E.L. Potter, R.J. Gorelick, C.L. Burch, K.M. Weeks and R. Swanstrom, <a href="https://www.ncbi.nlm.nih.gov/pubmed/23593004">Comparison of SIV and HIV-1 genomic RNA structures reveals impact of sequence evolution on conserved and non-conserved structural motifs</a>. <span class="italics">PLoS Path.</span> <span class="bold">9</span>, e1003294 (2013). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2013_ep_ppath.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 88 PDF">pdf</a></p> 426<p class="citation">87. D.M. Mauger, N.A. Siegfried and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/23499436">The genetic code as expressed through relationships between mRNA structure and protein function</a>. <span class="italics">FEBS Lett.</span> <span class="bold">587</span>, 1180-1188 (2013). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2013_dm_ns_febs.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 87 PDF">pdf</a></p> 427<p class="citation">86. C.E. Hajdin, S. Bellaousov, W. Huggins, C.W. Leonard, D.H. Mathews and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/23503844">Accurate SHAPE-directed RNA secondary structure modeling, including pseudoknots</a>. <span class="italics">Proc. Natl. Acad. Sci. USA</span> <span class="bold">110</span>, 5498-5503 (2013). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2013_ch_pnas.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 86 PDF">pdf</a> | <a href="https://webshare.oasis.unc.edu/weeksgroup/data-files/ShapeKnots_DATA.zip" target="_blank" rel="noopener noreferrer" aria-label="Publication number 86 zipped data download">data</a></p> 428<p class="citation">85. J.K. Grohman, R.J. Gorelick, C.R. Lickwar, J.D. Lieb, B.D. Bower, B.M. Znosko and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/23470731">A guanosine-centric mechanism for RNA chaperone function</a>. <span class="italics">Science</span> <span class="bold">340</span>, 190-195 (2013). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2013_jg_science.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 85 PDF">pdf</a></p> 429<p class="citation">84. S. Ramachandran, F. Ding, K.M. Weeks and N.V. Dokholyan, <a href="https://www.ncbi.nlm.nih.gov/pubmed/23286327">Statistical analysis of SHAPE-directed RNA secondary structure modeling</a>. <span class="italics">Biochemistry</span> <span class="bold">52</span>, 596-599 (2013). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2013_sr_bch.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 84 PDF">
429pdf</a></p> 430<p class="citation">83. C.W. Leonard, C.E. Hajdin, F. Karabiber, D.H. Mathews, O.V. Favorov, N.V. Dokholyan and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/23316814">Principles for understanding the accuracy of SHAPE-directed RNA structure modeling</a>. <span class="italics">Biochemistry</span> <span class="bold">52</span>, 588-595 (2013). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2013_cl_bch.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 83 PDF">pdf</a> | <a href="https://webshare.oasis.unc.edu/weeksgroup/data-files/Principles_DATA.zip" target="_blank" rel="noopener noreferrer" aria-label="Publication number 83 zipped data download">data</a></p> 431<p class="citation">82. F. Karabiber, J.L. McGinnis, O.V. Favorov and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/23188808"><span class="italics">QuShape</span>: Rapid, accurate and best-practices quantification of nucleic acid probing information, resolved by capillary electrophoresis</a>. <span class="italics">RNA</span> <span class="bold">19</span>, 63â73 (2013). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2013_fk_rna.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 82 PDF">pdf</a></p> 432<p><a href="https://www.chem.unc.edu/rna/qushape">software</a></p> 433<h3 class="year">2012</h3> 434<p class="citation">81. K.-A. Steen, G.M. Rice and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/22852530">Fingerprinting non-canonical and tertiary RNA structures by differential SHAPE reactivity</a>. <span class="italics">J. Am. Chem. Soc.</span> <span class="bold">134</span>, 13160-13163 (2012). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2012_ks_jacs.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 81 PDF">pdf</a></p> 435<p class="citation">80. F. Ding, C.A. Lavender, K.M. Weeks and N.V. Dokholyan, <a href="https://www.ncbi.nlm.nih.gov/pubmed/22504587">Three-dimensional RNA structure refinement by hydroxyl radical probing</a>. <span class="italics">Nature Meths.</span> <span class="bold">9</span>, 603-608 (2012). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2012_fd_al_nmeths.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 80 PDF">pdf</a></p> 436<p class="citation">79. J.L. McGinnis, J.A. Dunkle, J.H.D. Cate and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/22475022">The mechanisms of RNA SHAPE chemistry</a>. <span class="italics">J. Am. Chem. Soc.</span> <span class="bold">134</span>, 6617-6624 (2012). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2012_jm_jacs.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 79 PDF">pdf</a></p> 437<p class="citation">78. J.T. Low, S.A. Knoepfel, J.M. Watts, O. ter Brake, B. Berkhout and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/22314289">SHAPE-directed discovery of highly potent shRNA inhibitors of HIV-1</a>. <span class="italics">Mol. Ther.</span> <span class="bold">20</span>, 820-828 (2012). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2012_jl_molther.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 78 PDF">pdf</a></p> 438<p class="citation">77. J.A. Cruz <span class="italics">et al.</span> [C.A. Lavender, K.M. Weeks, and 29 others] and E. Westhof, <a href="https://www.ncbi.nlm.nih.gov/pubmed/22361291">RNA-Puzzles: A CASP-like evaluation of RNA three-dimensional structure prediction</a>. <span class="italics">RNA</span> <span class="bold">18</span>, 610-625 (2012). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2012_puzzles_rna.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 77 PDF">pdf</a></p> 439<h3 class="year">2011</h3> 440<p class="citation">76. J.K. Grohman, S. Kottegoda, R.J. Gorelick, N.L. Allbritton and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/22126209">Femtomole SHAPE reveals regulatory structures in the authentic XMRV RNA genome</a>. <span class="italics">J. Am. Chem. Soc.</span> <span class="bold">133</span>, 20326â20334 (2011). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2011_jg_jacs.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 76 PDF">pdf</a></p> 441<p class="citation">75. K.-A. Steen, N.A. Siegfried and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/21979276">
441Selective 2ʹ-hydroxyl acylation analyzed by protection from exoribonuclease (RNase-detected SHAPE) for direct analysis of covalent adducts and of nucleotide flexibility in RNA</a>. <span class="italics">Nature Protoc.</span> <span class="bold">6</span>, 1683-1694 (2011). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2011_ks_nprot.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 75 PDF">pdf</a></p> 442<p class="citation">74. K.M. Weeks and D.M. Mauger, <a href="https://www.ncbi.nlm.nih.gov/pubmed/21615079">Exploring RNA structural codes with SHAPE chemistry</a>. <span class="italics">Acc. Chem. Res.</span> <span class="bold">44</span>, 1280-1291 (2011). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2011_kw_acr.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 74 PDF">pdf</a></p> 443<p class="citation">73. K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/21700884">RNA structure probing <span class="italics">dash seq</span></a>. <span class="italics">Proc. Natl. Acad. Sci. USA</span> <span class="bold">108</span>, 10933-10934 (2011). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2011_kw_pnas.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 73 PDF">pdf</a></p> 444<p class="citation">72. P. Rocca-Serra <span class="italics">et al.</span> [C.D. Duncan, K.M. Weeks, and 13 others] and A. Laederach, <a href="https://www.ncbi.nlm.nih.gov/pubmed/21610212">Sharing and archiving nucleic acid structure mapping data</a>. <span class="italics">RNA</span> <span class="bold">17</span>, 1204-1212 (2011). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2011_snrnasm_rna.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 72 PDF">pdf</a></p> 445<h3 class="year">2010</h3> 446<p class="citation">71. D.M. Mauger and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/21057487">Toward global RNA structure analysis</a>. <span class="italics">Nature Biotech.</span> <span class="bold">28</span>, 1178-1179 (2010). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2010_dm_nbtech.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 71 PDF">pdf</a></p> 447<p class="citation">70. C. Gherghe, T. Lombo, C.W. Leonard, S.A.K. Datta, J.W. Bess, R.J. Gorelick, A. Rein and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/20974908">Definition of a high-affinity Gag recognition structure mediating packaging of a retroviral RNA genome</a>. <span class="italics">Proc. Natl. Acad. Sci. USA</span> <span class="bold">107</span>, 19248-19253 (2010). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2010_cg_pnas.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 70 PDF">pdf</a></p> 448<p class="citation">69. E. Simon-Loriere, D.P. Martin, K.M. Weeks and M. Negroni, <a href="https://www.ncbi.nlm.nih.gov/pubmed/20881047">RNA structures facilitate recombination-mediated gene swapping in HIV-1</a>. <span class="italics">J. Virol.</span> <span class="bold">84</span>, 12675-12682 (2010). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2010_esl_jvi.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 69 PDF">pdf</a></p> 449<p class="citation">68. K.-A. Steen, A. Malhotra and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/20597503">
449Selective 2ʹ-hydroxyl acylation analyzed by protection from exoribonuclease</a>. <span class="italics">J. Am. Chem. Soc.</span> <span class="bold">132</span>, 9940-9943 (2010). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2010_ks_jacs.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 68 PDF">pdf</a></p> 450<p class="citation">67. C.D.S. Duncan and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/20533823">Non-hierarchical ribonucleoprotein assembly suggests a strain-propagation model for protein-facilitated RNA folding</a>. <span class="italics">Biochemistry</span> <span class="bold">49</span>, 5418-5425 (2010). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2010_cd_bch.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 67 PDF">pdf</a></p> 451<p class="citation">66. J.T. Low and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/20554050">SHAPE-directed RNA secondary structure prediction</a>. <span class="italics">Methods</span> <span class="bold">52</span>, 150-158 (2010). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2010_jl_meths.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 66 PDF">pdf</a></p> 452<p class="citation">65. C.A. Lavender, F. Ding, N.V. Dokholyan and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/20545364">Robust and generic RNA modeling using inferred constraints: A structure for the hepatitis C virus IRES pseudoknot domain</a>. <span class="italics">Biochemistry</span> <span class="bold">49</span>, 4931-4933 (2010). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2010_al_bch.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 65 PDF">pdf</a></p> 453<p class="citation">64. C.E. Hajdin, F. Ding, N.V. Dokholyan and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/20498460">On the significance of an RNA tertiary structure prediction</a>. <span class="italics">RNA</span> <span class="bold">16</span>, 1340-1349 (2010). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2010_ch_rna.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 64 PDF">pdf</a></p> 454<p class="citation">63. K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/20447823">Advances in RNA structure analysis by chemical probing</a>. <span class="italics">Curr. Opin. Struct. Biol.</span> <span class="bold">20</span>, 295-304 (2010). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2010_kw_cosb.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 63 PDF">pdf</a></p> 455<p class="citation">62. C.D.S. Duncan and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/20126554">The Mrs1 splicing factor binds the bI3 group I intron at each of two tetraloop-receptor motifs</a>. <span class="italics">PLoS One</span> <span class="bold">5</span>, e8983 (2010). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2010_cd_pone.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 62 PDF">pdf</a></p> 456<p class="citation">61. C. Gherghe, C.W. Leonard, R.J. Gorelick and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/19889760">Secondary structure of the mature <i>ex virio</i> Moloney murine leukemia virus genomic RNA dimerization domain</a>. <span class="italics">J. Virol.</span> <span class="bold">84</span>, 898-906 (2010). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2010_cg_jvi.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 61 PDF">pdf</a></p> 457<h3 class="year">2009</h3> 458<p class="citation">60. J.L. McGinnis, C.D.S. Duncan and K.M. Weeks, High-throughput SHAPE and hydroxyl radical analysis of RNA structure and ribonucleoprotein assembly. <span class="italics">Methods Enzymol.</span> <span class="bold">468</span>, 67-89 (2009). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2009_jm_cd_mie.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 60 PDF">pdf</a></p> 459<p class="citation">59. S.A. Mortimer and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/19745823">Time-resolved RNA SHAPE chemistry: quantitative RNA structure analysis in one second snapshots and at single nucleotide resolution</a>. <span class="italics">Nature Protoc.</span> <span class="bold">4</span>, 1413-1421 (2009). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2009_sm_nprot.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 59 PDF">
459pdf</a></p> 460<p class="citation">58. S.A. Mortimer and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/19717440">C2′-endo nucleotides as molecular timers suggested by the folding of an RNA domain</a>. <span class="italics">Proc. Natl. Acad. Sci. USA</span> <span class="bold">106</span>, 15622-15627 (2009). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2009_sm_pnas.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 58 PDF">pdf</a></p> 461<p class="citation">57. J.M. Watts, K.K. Dang, R.J. Gorelick, C.W. Leonard, J.W. Bess, R. Swanstrom, C.L. Burch and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/19661910">Architecture and secondary structure of an entire HIV-1 RNA genome</a>. <span class="italics">Nature</span> <span class="bold">460</span>, 711-716 (2009). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2009_jw_nature.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 57 PDF">pdf</a> | <a href="https://webshare.oasis.unc.edu/weeksgroup/data-files/Watts_DATA.zip" target="_blank" rel="noopener noreferrer" aria-label="Publication number 57 zipped data download">data</a></p> 462<p class="citation">56. K.A. Wilkinson, S.M. Vasa, K.E. Deigan, S.A. Mortimer, M.C. Giddings and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/19458034">Influence of nucleotide identity on ribose 2′-hydroxyl reactivity in RNA</a>. <span class="italics">RNA</span> <span class="bold">15</span>, 1314-1321 (2009). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2009_kw_rna.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 56 PDF">pdf</a></p> 463<p class="citation">55. S.A. Mortimer, J.S. Johnson and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/19226117">Quantitative analysis of RNA solvent accessibility by N-silylation of guanosine</a>. <span class="italics">Biochemistry</span> <span class="bold">48</span>, 2109-2114 (2009). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2009_sm_bch.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 55 PDF">pdf</a></p> 464<p class="citation">54. C.M. Gherghe, C.W. Leonard, F. Ding, N.V. Dokholan and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/19193004">Native-like RNA tertiary structures using a sequence-encoded cleavage agent and refinement by discrete molecular dynamics</a>. <span class="italics">J. Am. Chem. Soc.</span> <span class="bold">131</span>, 2541-2546 (2009). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2009_cg_jacs.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 54 PDF">pdf</a></p> 465<p class="citation">53. K.E. Deigan, T.W. Li, D.H. Mathews and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/19109441">Accurate SHAPE-directed RNA structure determination</a>. <span class="italics">Proc. Natl. Acad. Sci. USA</span> <span class="bold">106</span>, 97-102 (2009). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2009_kd_pnas.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 53 PDF">pdf</a> | <a href="https://webshare.oasis.unc.edu/weeksgroup/data-files/Deigan_DATA.zip" target="_blank" rel="noopener noreferrer" aria-label="Publication number 53 zipped data download">data</a></p> 466<h3 class="year">2008</h3> 467<p class="citation">52. S.A. Mortimer and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/18998638">Time-resolved RNA SHAPE chemistry</a>. <span class="italics">J. Am. Chem. Soc.</span> <span class="bold">130</span>, 16178-16180 (2008). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2008_sm_jacs.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 52 PDF">pdf</a></p> 468<p class="citation">51. T.S. Maity, H.M. Fried and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/18564060">Anti-cooperative assembly of the SRP19 and SRP68/72 components of the signal recognition particle</a>. <span class="italics">Biochem. J.</span> <span class="bold">415</span>, 429-437 (2008). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2008_tm_bj.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 51 PDF">pdf</a></p> 469<p class="citation">50. S.M. Vasa, N. Guex, K.A. Wilkinson, K.M. Weeks and M.C. Giddings, <a href="https://www.ncbi.nlm.nih.gov/pubmed/18772246">ShapeFinder: A software system for high-throughput quantitative analysis of nucleic acid reactivity information resolved by capillary electrophoresis</a>. <span class="italics">RNA</span> <span class="bold">14</span>, 1979-1990 (2008). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2008_sv_ng_r
469na.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 50 PDF">pdf</a></p> 470<p class="citation">49. C.M. Gherghe, Z. Shajani, K.A. Wilkinson, G. Varani and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/18710236">Strong correlation between SHAPE chemistry and the generalized NMR order parameter (S<sup>2</sup>) in RNA</a>. <span class="italics">J. Am. Chem. Soc.</span> <span class="bold">130</span>, 12244-12245 (2008). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2008_cg_jacs_S2.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 49 PDF">pdf</a></p> 471<p class="citation">48. C.D.S. Duncan and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/18642882">SHAPE analysis of long-range interactions reveals extensive and thermodynamically preferred misfolding in a fragile group I intron RNA</a>. <span class="italics">Biochemistry</span> <span class="bold">47</span>, 8504-8513 (2008). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2008_cd_bch.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 48 PDF">pdf</a></p> 472<p class="citation">47. C.M. Gherghe, S.A. Mortimer, J.M. Krahn, N.L. Thompson and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/18558680">Slow conformational dynamics at C2′-endo nucleotides in RNA</a>. <span class="italics">J. Am. Chem. Soc.</span> <span class="bold">130</span>, 8884-8885 (2008). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2008_cg_jacs_C2.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 47 PDF">pdf</a></p> 473<p class="citation">46. K.A. Wilkinson, R.J. Gorelick, S.M. Vasa, N. Guex, A. Rein, D.H. Mathews, M.C. Giddings and K.M. Weeks, <a href="https://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0060096">High-throughput SHAPE analysis reveals structures in HIV-1 genomic RNA strongly conserved across distinct biological states</a>. <span class="italics">PLoS Biology</span> <span class="bold">6</span>, e96 (2008). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2008_kw_pbio.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 46 PDF">pdf</a> | <a href="https://webshare.oasis.unc.edu/weeksgroup/data-files/Wilkinson_DATA.xls.zip" target="_blank" rel="noopener noreferrer" aria-label="Publication number 46 zipped data download">data</a></p> 474<p class="citation">45. C.N. Jones, K.A. Wilkinson, K.T. Hung, K.M. Weeks and L.L. Spremulli, <a href="https://www.ncbi.nlm.nih.gov/pubmed/18367717">Lack of secondary structure characterizes the 5′ ends of mammalian mitochondrial mRNAs</a>. <span class="italics">RNA</span> <span class="bold">14</span>, 862-871 (2008). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2008_cj_rna.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 45 PDF">pdf</a></p> 475<p class="citation">44. B. Wang, K.A. Wilkinson and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/18290632">Complex ligand-induced conformational changes in tRNA<sup>Asp</sup> revealed by single nucleotide resolution SHAPE chemistry</a>. <span class="italics">Biochemistry</span> <span class="bold">47</span>, 3454-3461 (2008). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2008_bw_bch.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 44 PDF">pdf</a></p> 476<h3 class="year">2007</h3> 477<p class="citation">43. T.S. Maity and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/17434535">A three-fold RNA-protein interface in the signal recognition particle gates native complex assembly</a>. <span class="italics">J. Mol. Biol.</span> <span class="bold">369</span>, 512-524 (2007). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2007_tm_jmb.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 43 PDF">pdf</a></p> 478<p class="citation">42. S.A. Mortimer and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/17367143">A fast acting reagent for accurate analysis of RNA secondary and tertiary structure by SHAPE chemistry</a>. <span class="italics">J. Am. Chem. Soc.</span> <span class="bold">129</span>, 4144-4145 (2007). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2007_sm_jacs.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 42 PDF">
478pdf</a></p> 479<h3 class="year">2006</h3> 480<p class="citation">41. C. Gherghe and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/16984912">The SL1-SL2 (stem-loop) domain is the primary determinant for stability of the gamma retroviral genomic RNA dimer</a>. <span class="italics">J. Biol. Chem.</span> <span class="bold">281</span>, 37952-37961 (2006). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2006_cg_jbc.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 41 PDF">pdf</a></p> 481<p class="citation">40. T.S. Maity, C.W. Leonard, M.A. Rose, H.M. Fried and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/17154533">Compartmentalization directs assembly of the signal recognition particle</a>. <span class="italics">Biochemistry</span> <span class="bold">45</span>, 14955-14964 (2006). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2006_tm_bch.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 40 PDF">pdf</a></p> 482<p class="citation">39. K.A. Wilkinson, E.J. Merino and K.M. Weeks, <a href="https://doi.org/10.1038/nprot.2006.249">Selective 2′-hydroxyl acylation analyzed by primer extension (SHAPE): quantitative RNA structure analysis at single nucleotide resolution</a>. <span class="italics">Nature Protoc.</span> <span class="bold">1</span>, 1610-1616 (2006). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2006_kw_nprot.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 39 PDF">pdf</a></p> 483<p class="citation">38. C.S. Badorrek and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/17042483">Architecture of a gamma retroviral genomic RNA dimer</a>. <span class="italics">Biochemistry</span> <span class="bold">45</span>, 12664-12672 (2006). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2006_cb_bch.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 38 PDF">pdf</a></p> 484<p class="citation">37. C.S. Badorrek, C.M. Gherghe and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/16945907">Structure of an RNA switch that enforces stringent retroviral genomic RNA dimerization</a>. <span class="italics">Proc. Natl. Acad. Sci. USA</span> <span class="bold">103</span>, 13640-13645 (2006). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2006_cb_pnas.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 37 PDF">pdf</a></p> 485<p class="citation">36. G. Bokinsky, L.G. Nivon, S. Liu, G. Chai, M. Hong, K.M. Weeks and X. Zhuang, <a href="https://www.ncbi.nlm.nih.gov/pubmed/16872630">Two distinct binding modes of a protein cofactor with its target RNA</a>. <span class="italics">J. Mol. Biol.</span> <span class="bold">361</span>, 771-784 (2006). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2006_gb_xz_jmb.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 36 PDF">pdf</a></p> 486<p class="citation">35. T.W. Li and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/16325753">Structure-independent and quantitative ligation of single-stranded DNA</a>. <span class="italics">Anal. Biochem.</span> <span class="bold">349</span>, 242-246 (2006). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2006_tl_analbio.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 35 PDF">pdf</a></p> 487<h3 class="year">2005</h3> 488<p class="citation">34. C.M. Gherghe, J.M. Krahn and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/16190727">Crystal structures, reactivity and inferred acylation transition states for 2′-amine substituted RNA</a>. <span class="italics">J. Am. Chem. Soc.</span> <span class="bold">127</span>, 13622-13628 (2005). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/gherghe_supp_info.qt">Supplementary Movie</a> | <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2005_cg_jacs.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 34 PDF">
488pdf</a></p> 489<p class="citation">33. E.J. Merino and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/16159247">Facile conversion of aptamers into sensors using a 2′-ribose linked fluorophore</a>. <span class="italics">J. Am. Chem. Soc.</span> <span class="bold">127</span>, 12766-12767 (2005). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2005_em2_jacs.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 33 PDF">pdf</a></p> 490<p class="citation">32. A. Longo, C.W. Leonard, G.S. Bassi, D. Berndt, J.M. Krahn, T.M.T. Hall and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/16116439">Evolution from DNA to RNA recognition by the bI3 LAGLIDADG maturase</a>. <span class="italics">Nature Struct. Mol. Biol.</span> <span class="bold">12</span>, 779-787 (2005). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2005_al_nsmb.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 32 PDF">pdf</a></p> 491<p class="citation">31. C.L. Badorrek and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/16408007">RNA flexibility in the dimerization domain of a gamma retrovirus</a>. <span class="italics">Nature Chem. Biol.</span> <span class="bold">1</span>, 104-111 (2005). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2005_cb_nchemb.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 31 PDF">pdf</a></p> 492<p class="citation">30. K.A. Wilkinson, E.J. Merino and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/15796531">RNA SHAPE chemistry reveals non-hierarchical interactions dominate equilibrium structural transitions in tRNA<sup>Asp</sup> transcripts</a>. <span class="italics">J. Am. Chem. Soc.</span> <span class="bold">127</span>, 4659-4667 (2005). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2005_kw_jacs.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 30 PDF">pdf</a></p> 493<p class="citation">29. E.J. Merino, K.A. Wilkinson, J.L. Coughlan and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/15783204">RNA structure analysis at single nucleotide resolution by Selective 2′-Hydroxyl Acylation and Primer Extension (SHAPE)</a>. <span class="italics">J. Am. Chem. Soc.</span> <span class="bold">127</span>, 4223-4231 (2005). <a href="https://webshare.oasis.unc.edu/weeksgroup/pdf-files/2005_em_jacs.pdf" target="_blank" rel="noopener noreferrer" aria-label="Publication number 29 PDF">pdf</a></p> 494<h3 class="year">2004</h3> 495<p class="citation">28. K.L. Buchmueller and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/15601995">Tris-borate is a poor counterion for RNA: a cautionary tale for RNA folding studies</a>. <span class="italics">Nucl. Acids Res.</span> <span class="bold">32</span>, e184 (6 pp.) (2004).</p> 496<p class="citation">27. I. Garcia and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/15568809">Structural basis for the self-chaperoning function of an RNA collapsed state</a>. <span class="italics">Biochemistry</span> <span class="bold">43</span>, 15179-15186 (2004).</p> 497<p class="citation">26. D.M. John, E.J. Merino and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/15019781">Mechanics of DNA flexibility visualized by selective 2′-amine acylation at nucleotide bulges</a>. <span class="italics">J. Mol. Biol.</span> <span class="bold">337</span>, 611-619 (2004).</p> 498<h3 class="year">2003</h3> 499<p class="citation">25. K.L. Buchmueller and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/14636054">Near native structure in an RNA collapsed state</a>. <span class="italics">Biochemistry</span> <span class="bold">42</span>, 13869-13878 (2003).</p> 500<p class="citation">24. E.J. Merino and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/14531655">Fluorogenic resolution of ligand binding by a nucleic acid aptamer</a>. <span class="italics">J. Am. Chem. Soc.</span> <span class="bold">125</span>, 12370-12371 (2003).</p> 501<p class="citation">23. K.L. Buchmueller, B.T. Hill, M.S. Platz and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/12952464">RNA-tethered phenylazide photocrosslinking via a short-lived indiscriminant electrophile</a>. <span class="italics">J. Am. Chem. Soc.</span> <span class="bold">125</span>, 10850-10861 (2003).</p> 502<p class="citation">22. G.S. Bassi and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/12924947">A kinetic and thermodynamic framework for assembly of the six-component bI3 group I intron ribonucleoprotein catalyst</a>. <span class="italics">Biochemistry</span> <span class="bold">42</span>, 9980-9988 (2003).</p> 503<p class="citation">21. I. Garcia and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/12875836">Small structural costs for evolution from RNA to RNP-based catalysis</a>. <span class="italics">J. Mol. Biol.</span> <span class="bold">331</span>, 57-73 (2003).</p> 504<p class="citation">20. S.I. Chamberlin and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/12549908">Differential helix stabilities and sites pre-organized for tertiary interactions revealed by monitoring local nucleotide flexibility in the bI5 group I intron RNA</a>. <span class="italics">Biochemistry</span> <span class="bold">42</span>, 901-909 (2003).</p> 505<h3 class="year">2002</h3> 506<p class="citation">19. S.I. Chamberlin, E.J. Merino and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/12403820">Catalysis of amide synthesis by RNA phosphodiester and hydroxyl groups</a>. <span class="italics">Proc. Natl. Acad. Sci. USA</span> <span class="bold">99</span>, 14688-14693 (2002).</p> 507<p class="citation">18. D.M. John and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/12022892">Chemical interrogation of mismatches in DNA-DNA and DNA-RNA duplexes under non-stringent conditions by selective 2′-amine acylation</a>. <span class="italics">Biochemistry</span> <span class="bold">41</span>, 6866-6874 (2002).</p> 508<p class="citation">17. G.S. Bassi, D.M. de Oliviera, M.F. White and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/11773622">Recruitment of intron encoded and co-opted proteins in splicing of the bI3 group I intron RNA</a>. <span class="italics">Proc. Natl. Acad. Sci. USA</span> <span class="bold">99</span>, 128-133 (2002).</p> 509<h3 class="year">2001</h3> 510<p class="citation">16. A.E. Webb, M.A. Rose, E. Westhof and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/11399081">Protein-dependent transition states for ribonucleoprotein assembly</a>. <span class="italics">J. Mol. Biol.</span> <span class="bold">309</span>, 1087-1100 (2001).</p> 511<p class="citation">15. M.A. Rose and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/11373619">Visualizing induced fit in early assembly of the human signal recognition particle</a>. <span class="italics">Nature Struct. Biol.</span> <span class="bold">8</span>, 515-520 (2001).</p> 512<p class="citation">14. A.E. Webb and K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/11175902">
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Biol.</span> <span class="bold">7</span>, 362-366 (2000).</p> 517<p class="citation">10. S.I. Chamberlin and K.M. Weeks, <a href="https://doi.org/10.1021/ja9914137">Mapping local nucleotide flexibility by selective acylation of 2′-amine substituted RNA</a>. <span class="italics">J. Am. Chem. Soc.</span> <span class="bold">122</span>, 216-224 (2000).</p> 518<h3 class="year">Pre-2000</h3> 519<p class="citation">9. K.M. Weeks, <a href="https://www.ncbi.nlm.nih.gov/pubmed/9204274">Protein-facilitated RNA folding</a>. <span class="italics">Curr. Opin. Struct. Biol.</span> <span class="bold">7</span>, 336-342 (1997).</p> 520<p class="citation">8. K.M. Weeks and T.R. Cech, <a href="https://www.ncbi.nlm.nih.gov/pubmed/8553068">Assembly of a ribonucleoprotein catalyst by tertiary structure capture</a>. <span class="italics">Science</span> <span class="bold">271</span>, 345-348 (1996).</p> 521<p class="citation">7. K.M. Weeks and T.R. Cech, <a href="https://www.ncbi.nlm.nih.gov/pubmed/7628013">Protein facilitation of group I intron splicing by assembly of the catalytic core and the 5′ splice site domain</a>. <span class="italics">Cell</span> <span class="bold">82</span>, 221-230 (1995).</p> 522<p class="citation">6. K.M. Weeks and T.R. Cech, <a href="https://www.ncbi.nlm.nih.gov/pubmed/7540041">Efficient protein-facilitated splicing of the yeast mitochondrial bI5 intron</a>. <span class="italics">Biochemistry</span> <span class="bold">34</span>, 7728-7738 (1995).</p> 523<p class="citation">5. K.M. Weeks and D.M. Crothers, <a href="https://www.ncbi.nlm.nih.gov/pubmed/7690496">Major groove accessibility of RNA</a>. <span class="italics">Science</span> <span class="bold">261</span>, 1574-1577 (1993).</p> 524<p class="citation">4. K.M. Weeks and D.M. Crothers, RNA Targeting by the HIV-1 Tat Protein. <span class="italics">Persp. in Drug Discovery and Design</span> <span class="bold">1</span>, 225-234 (1993).</p> 525<p class="citation">3. K.M. Weeks and D.M. Crothers, <a href="https://www.ncbi.nlm.nih.gov/pubmed/1384694">RNA binding assays for Tat-derived peptides: implications for specificity</a>. <span class="italics">Biochemistry</span> <span class="bold">31</span>, 10281-10287 (1992).</p> 526<p class="citation">2. K.M. Weeks and D.M. Crothers, <a href="https://www.ncbi.nlm.nih.gov/pubmed/1907891">RNA recognition by Tat-derived peptides: interaction in the major groove</a>? <span class="italics">Cell</span> <span class="bold">66</span>, 577-588 (1991); <span class="bold">70</span>, 1069.</p> 527<p class="citation">1. K.M. Weeks, C. Ampe, S.C. Schultz, T.A. Steitz and D.M. Crothers, <a href="https://www.ncbi.nlm.nih.gov/pubmed/2205002">Fragments of the HIV-1 Tat protein specifically bind TAR RNA</a>. <span class="italics">Science</span> <span class="bold">249</span>, 1281-1285 (1990).</p> 528</div> 529 530 531 </main><!-- /.main --> 532 </div> 533 </div><!-- /.content --> 534 </div><!-- /.wrap --> 535 <div class="row"> 536 </div> 537 538 <div class="row"> 539 <footer class="content-info"> 540 <div class="footer-container container"> 541 <div class="row"> 542 <section class="widget_text widget custom_html-5 widget_custom_html col-md-4 col-sm-6"><div class="textwidget custom-html-widget"><strong>Kevin Weeks, Ph.D.</strong><br> 543Department of Chemistry, CB-3290<br> 544University of North Carolina<br> 545Chapel Hill, NC 27599-3290<br> 546 547 548<br> 549<i class="bi bi-telephone-fill" aria-label="phone"></i> 919-962-7486 - Office<br> 550<i class="bi bi-telephone-fill" aria-label="phone"></i> 919-962-2184 - Laboratory<br> 551<i class="bi bi-envelope-fill" aria-label="email"></i> <a href="mailto:[email protected]">[email protected]</a></div></section><section class="widget_text widget custom_html-6 widget_custom_html col-md-4 col-sm-6"><div class="textwidget custom-html-widget"></div></section><section class="widget media_image-5 widget_media_image col-md-4 col-sm-6"><img width="2324" height="376" src="https://weekslab.org/wp-content/uploads/sites/4127/2019/10/chem_logo_light.png" class="image wp-image-199 attachment-full size-full" alt="Department of Chemistry Logo" style="max-width: 100%; height: auto;" decoding="async" loading="lazy" srcset="https://weekslab.org/wp-content/uploads/sites/4127/2019/10/chem_logo_light.png 2324w, https://weekslab.org/wp-content/uploads/sites/4127/2019/10/chem_logo_light-300x49.png 300w, https://weekslab.org/wp-content/uploads/sites/4127/2019/10/chem_logo_light-1024x166.png 1024w, https://weekslab.org/wp-content/uploads/sites/4127/2019/10/chem_logo_light-768x124.png 768w, https://weekslab.org/wp-content/uploads/sites/4127/2019/10/chem_logo_light-1536x249.png 1536w, https://weekslab.org/wp-content/uploads/sites/4127/2019/10/chem_logo_light-2048x331.png 2048w" sizes="auto, (max-width: 2324px) 100vw, 2324px" /></section> 552 </div> 553 </div> 554 <div id="copyright"> 555 <p class="copyright">© 2026 Weeks Lab</p> 556 </div> 557</footer>
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